From reading too much, and sleeping too little, his brain dried up on him and he lost his judgment.

It is bad judgment to speak of halters in the house of a man who was hanged

Y así, del poco dormir y del mucho leer se le secó el cerebro, de manera que vino a perder el juicio.

Finally, from so little sleeping and so much reading, his brain dried up and he went completely out of his mind.

El ver mucho y leer mucho aviva los ingenios de los hombres.

From reading too much, and sleeping too little, his brain dried up on him and he lost his judgment.