I am afraid we cannot say our remedy has had any real impact, as far as we can see.

Lots of famous people wrote big articles saying tumors are not recognized by the immune system. We were not so famous, but we thought maybe they were wrong.

The bottom just fell out of it.

We didn't know what to do. We felt kind of obsolete.

A boom doesn't last forever and it doesn't go the other way for very long either.

Although the market will be particularly challenging in the beginning of 2002 we maintain our objective of over five percent operating margin for the full year.