If you thought financial crises came and went, just count on them - another economic collapse, it's almost going to be like not news any more. But for startups this is great, because it's a perpetual driver of disruption.

The future will be less predictable, forecast rises will shrink, company lifetimes will shrink, new entrants will proliferate and it's going to just get more unpredictable.

Biotech 1.0 is slow, like a lab science, and Version 2.0 is more like computational sciences.

Eventually, all cars are going to be autonomous.

SpaceX lowered the cost of going into space by 10x.

My interest in space started early, but for many years, I could not find any space-related investments that really penciled-out for venture. That changed in 2009 when Elon Musk came to us with a big vision to explore Mars while producing rockets at a fraction of a price and making space accessible.