Our strong first quarter top-line performance reflects a healthy business across the board. Moving forward we will continue to invest in our existing businesses and R&D pipeline.

2005 was a year of continued growth and business expansion. Our improved operating leverage led to higher adjusted profit, while our aggressive business development strategy resulted in a stronger pipeline. During 2006, we will maintain our focus on maximizing the potential of our marketed products, the efficiency of our business operations and the advancement of our most promising clinical programs.

You can't change who you are, but you can change what you have in your head, you can refresh what you're thinking about, you can put some fresh air in your brain.

I really enjoy sailing on Lake Geneva because I can just look at the shore and see my wife having a barbecue with the kids.

My father was a sailor and our summer vacations were always on a sailboat. I had a little boat before I had a moped.

It is clear we cannot stand still.