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Our study shows that DNA itself can act as a mutagen, resulting in genetic instability. The discovery opens up a new field of inquiry into the role of DNA shape in genomic instability and cancer.


Karen Vasquez

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The hundreds and hundreds of African-American women participating in the Carolina Breast Cancer Stud...
JEFFREY CANTER Here at the Cold Spring Harbor Laboratory, we have genetically rearranged various viruses and bacter...
JAMES D. WATSON We actually fold the DNA into any shape that we want. So in the case of the smiley faces that I made...
PAUL ROTHEMUND DNA is not like videotape. DNA doesn't show you what happened in the past. At most, DNA can show som...
ROBERT ANDREWS This discovery sheds new light on the biological causes of the disease. Importantly, virtually all o...
KARI STEFANSSON Because the thing about viruses is that they're easily manipulated. The DNA they inject doesn't have...
CHRISTIAN CANTRELL DNA is the master blueprint for life and constitutes the genetic material in all free-living organis...
RICHARD J. ROBERTS This last discovery illuminated the mechanism of protein synthesis: the protein chain is transferred...
WALTER GILBERT One's ideas must be as broad as Nature if they are to interpret Nature
ARTHUR CONAN DOYLE The new data show that protons produce more potentially lethal double-strand breaks, a type of sever...
BETSY SUTHERLAND Our discovery shows that nature has provided at least two completely different methods to generate a...
JASON MILLER Transposons are just small pieces of DNA that randomly insert in the genetic code. And if they inser...
CRAIG VENTER An important finding is that by determining the genome sequences of an entire family, one can identi...
LEROY HOOD We think that Kosovo will continue to serve as a centre of violence and regional instability in futu...
BORIS TRAJKOVSKI What we create online becomes part of our digital DNA, this in turns becomes part of our human DNA.
TIFFANY SUNDAY While genes are pivotal in establishing some aspects of emotionality, experience plays a central rol...
THOMAS LEWIS The cloning procedure is similar to IVF. The only difference is that the DNA of sperm and egg would ...
NATHAN MYHRVOLD It seems likely that most if not all the genetic information in any organism is carried by nucleic a...
FRANCIS CRICK The discovery opened up a whole new field of physics and expanded our understanding of particle phys...
HERBERT STEINER DNA gets everywhere. So when we're dealing with a sample and you find it's got human DNA in it - is ...
CHRIS STRINGER It's just unsettling to have our DNA in a highly unsecured environment like the public mails. Once a...
GREG FOWLER You must save what you can of your life; you musn't lose it all simply because you've lost a part.
HENRY JAMES Well, Nigeria has played a constructive role in peacekeeping in various parts of West Africa. But un...
SUSAN RICE Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to ge...
SAM KEAN You're full of contradictions, Ms. Wallace."
I looked up at him and arched a brow. "I'm a girl...
TAMMARA WEBBER The only way he could have her was to shatter this stubborn faith of hers. In doing so, would he sha...
FRANCINE RIVERS Thank goodness for DNA. DNA makes it a safer world. Let's hope the prosecutor will put much stock in...
WADE SMITH Exactly 100 years after Einstein first explained this effect, we have found a way to make it useful ...
GELSOMINA DE STASIO It will be an important step in our understanding of the genetic components of cancer and the geneti...
ANDREW ESCHENBACH It will be an important step in our understanding of the genetic components of cancer and the geneti...
ANDREW C. VON ESCHENBACH So, there is enormous instability in the global economy with a shift of winners and losers.
DAVID KORTEN If I provide for this life and turn away from the Lord, I am wise for a moment, but lost forever.
FRANCINE RIVERS The only way he could have her was to shatter this stubborn faith of hers. In doing so, would he sha...
FRANCINE RIVERS The ball can change hands a thousand-plus times, but it will never lose that DNA. The chance of repl...
JOE ORLANDO Importantly, virtually all of this risk can be captured by looking at a single-letter change in DNA ...
KARI STEFANSSON In an age of molecular genomics, it is ever more apparent that the fingerprints of evolution are pre...
KENNETH R. MILLER Empathy is the new measurement of everything. It doesn't matter what religion you have, what God you...
C. JOYBELL C. During this period, I became interested in how the new techniques of cloning and sequencing DNA coul...
SYDNEY BRENNER Whatever has overstepped its due bounds is always in a state of instability.
SENECA (SENECA THE ELDER) Whatever has overstepped its due bounds is always in a state of instability.
SENECA But chastity means passion, chastity means neurasthenia. And passion and neurasthenia mean instabili...
ALDOUS HUXLEY With genetic engineering, we will be able to increase the complexity of our DNA, and improve the hum...
STEPHEN HAWKING The Constitution itself, the DNA of the country, can be altered by the collective will of the people...
BRYANT MCGILL This was a discovery study that established the concept of taking advantage of the immune system to ...
ARUL CHINNAIYAN There is no DNA evidence that shows she was touched by any of these boys.
JOE CHESHIRE Cancer is a disease of the genome. And that's what happens. You make mistakes in a cell somewher...
FRANCIS COLLINS We have to bring stability to Iraq, otherwise we will be faced with a future dilemma of sending our ...
JAY ROCKEFELLER She wasn't bitter. She was sad, though. But it was a hopeful kind of sad. The kind of sad that just ...
STEPHEN CHBOSKY So, I guess we are who we are for alot of reasons. And maybe we'll never know most of them. But even...
STEPHEN CHBOSKY I love my mom so much. I don't care if that's corny to say. I think on my next birthday, I'm going t...
STEPHEN CHBOSKY We Are All Infinite
STEPHEN CHBOSKY (All the grief she had suffered over her lifetime had moulded her face into a mask of eternal sadnes...
JEAN SASSON You can't just sit there and put everyone's lives ahead of yours and think that counts as love. You ...
STEPHEN CHBOSKY I saw other people there. Old men sitting alone. Young girls with blue eye shadow and awkward jaws. ...
STEPHEN CHBOSKY That one moment when you know you are not a sad story. You are ALIVE.
STEPHAN CHBOSKY Somos quienes somos por un montón de razones.Quizás nunca conozcamos la mayoría de ellas.Pero aun...
STEPHEN CHBOSKY Ambos dijeron que tomara asiento y parecían hablar en serio, así que me senté.
STEPHEN CHBOSKY I know these will all be stories some day, and our pictures will become old photographs. We all beco...
STEPHEN CHBOSKY So I guess we are who we are for a lot of reasons. And maybewe'll never know most of them.
STEPHEN CHBOSKY So I guess we are who we are for a lot of reasons. And maybe we'll never know most of them.
STEPHEN CHBOSKY There's nothing like the deep breathes after laughing that hard. Nothing in the world like a sore st...
STHEPHEN CHBOSKY no more pencils, no more books, no more teachers' dirty looks, when the teacher rings the bell, drop...
STEPHEN CHBOSKY I don't know the significance of this, but I find it very interesting.
STEPHEN CHBOSKY Maybe it’s sad that these are now memories. And maybe it’s not sad.
STEPHEN CHBOSKY Never give up on you. In order to make a difference you would have to somehow be different.
JOHNNIE DENT JR. Bush knows that Berlusconi will lose, and is giving him a farewell party. This new legislature may b...
MASSIMO FRANCO You deserve to be with somebody, who knows you're the one, from that very first moment he lays eyes ...
C. JOYBELL C. We know that one of the functions of the BRCA1 and BRCA2 genes is to maintain genomic integrity, and...
ELIOT ROSEN Broccoli is incredible. It can prevent DNA damage and metastatic cancer spread; activate defences ag...
MICHAEL GREGER If the crisis continues, it could create an image of instability and uncertainty in Thailand.
PANITAN WATTANAYAGORN That's what New Orleans does. It's part of our DNA, the whole idea of going a little crazy to keep y...
FRED LEBLANC One of the greatest advantages of being an empath is that experiencing a spiritual awakening is virt...
ALETHEIA LUNA The issue of pollution has become a blasting fuse for social instability.
ZHOU SHENGXIAN I realized that day that blessings come in a variety of shapes, colors, and sizes.
CRAIG GROESCHEL We mark them with a synthetic DNA strand that can only be seen with a special laser frequency, calib...
JOE ORLANDO Our experimental results agreed with the computational findings, indicating that these ratchetting p...
JAVIER LOPEZ It was so new, I had never heard of DNA other than seeing something in the paper that something is c...
ALAN COLEMAN As Ethiopia goes, so goes the whole Horn of Africa - a region where instability can have major secur...
ESKINDER NEGA Philanthropy is in the DNA of my family.
CHARLES BRONFMAN There is no better time to become known than in the time of crisis and instability
SUNDAY ADELAJA The ability to observe what happens to electronic energy in DNA on such short time scales also exten...
BERN KOHLER I am still in a little bit of shock. I was beaten up for two days on the stand years ago (by an aggr...
KATHLEEN HAM We have the DNA of our Lord Jesus Christ.
HERSCHEL WALKER As far as DNA testing, we're just at the beginning of that universe. Pretty soon, though, we'll know...
ALAN MILSTEIN What enables one person to launch a business at fifty when other people, faced with being laid off, ...
L. HARRISON As discomfiting as it is to both market optimists and policy activists, a certain amount of instabil...
VIRGINIA POSTREL The pieces of DNA you find in the Y-chromosome don't go through the same shuffling process that othe...
SPENCER WELLS Wake up to a brand new day and realize why you woke up to meet the day! Live to the end of another d...
ERNEST AGYEMANG YEBOAH One little natural disaster, a refinery fire, any type of instability in various parts of the world ...
MANTILL WILLIAMS In my early work, our molecular views of telomeres were first focused on the DNA.
ELIZABETH BLACKBURN With a hundred and seventy-eight machines to sequence the precise order of the billions of chemicals...
MICHAEL SPECTER Our average DNA case is a minimum of a month or more.
ANNETTE DAVIS SEQuester(tm), the patented star product in this new generation of super filters, is intended for th...
KENT JOHNSON If employers could give employees DNA tests, then they could find out if there's a propensity for il...
ALAN MILSTEIN This asymmetry in the treatment of lenders and borrowers is a major source of instability in the glo...
GEORGE SOROS Glaciers are delicate and individual things, like humans. Instability is built into them.
WILL HARRISON If this blows up, it could usher a period of economic weakening and political instability. This deve...
EARL PARRENO There's almost no food that isn't genetically modified. Genetic modification is the basis of...
NINA FEDOROFF We can pattern a surface with single-stranded DNA containing a specific nucleotide sequence, then co...
RAVI CHANDRA Everything a person is and everything he knows resides in the tangled thicket of his intertwined neu...
THOMAS LEWIS

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KAREN KAIN Friday night is our date night. We really carve out time for each other.
KAREN KAIN The facts are on our side.
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KAREN ELSON Research on the Internet, research what people say about the vintage stores, look online to see if c...
KAREN ELSON As a model, I am at the mercy of everybody else. It's much more of a situation where I go to wor...
KAREN ELSON Think about your menu, and if you're not a skilled chef - which I'm not - follow a recipe. Y...
KAREN ELSON I feel Dress for Success is basically about empowering women who were in a disadvantaged situation. ...
KAREN ELSON I love Jen Meyer - she's a dear friend, and Tabitha Simmons as well.
KAREN ELSON I like those stories that capture the brutality of life, but there's still some kind of melancho...
KAREN ELSON I tend to sort of over-accessorize, but to feel empowered, I strip it all down and become minimal so...
KAREN ELSON I had a diary full of lyrics and whatnot and a little voice recorder of guitar riffs.
KAREN ELSON I'm a fan of creating the mood and vibe with flowers, candles, and music. I love making my guest...
KAREN ELSON I am obsessed with the Great Depression and with former showgirls - and the Victorians - the idea of...
KAREN ELSON As scary as it is, I like making real, direct eye contact with people from the stage. In a sense, it...
KAREN ELSON I constantly have a devil on my shoulder telling me that what I'm doing is really horrible, and ...
KAREN ELSON The interesting thing with fashion is that it's really a massive daydream.
KAREN ELSON I have lots and lots of party clothes. I mean real party clothes.
KAREN DUFFY You become a parent when you have a baby, no matter how you get there.
KAREN DUFFY My father managed shopping malls when I was a kid, and my high school job was to dress up in an elf ...
KAREN DUFFY I am a bit of a Cheap Pete, but I do spend a fortune on books and false moustaches and practical jok...
KAREN DUFFY I am enormously honored to be one of the spokesmen of the New Age Womens Health Campaign, so you'...
KAREN DUFFY I don't have feeling in my feet to my fingertips; I also have active lesions in my bone marrow a...
KAREN DUFFY In the beginning, when I first found out I had a disease that was incurable, emotionally I had to ge...
KAREN DUFFY I just had that conversation this morning with my doctor. I just got back from the hospital a half-h...
KAREN DUFFY My family has been amazing, and they understand how blessed I am. They've been able to keep my s...
KAREN DUFFY Everyone who has sarcoidosis is affected differently.
KAREN DUFFY In addition, I'll be attending women's health expos and medical conferences with the goal to...
KAREN DUFFY A lot of people asked me if it was frustrating not having a clear specific diagnosis, but I didn'...
KAREN DUFFY