Single molecule absorption spectroscopy is an extremely sensitive technique for analytical chemistry, for measuring electrical properties of molecules, and for studying energy transfer on surfaces. While most molecules don't fluoresce -- limiting the usefulness of single molecule fluorescence spectroscopy -- all molecules absorb, making single molecule absorption spectroscopy a much more general approach.
Martin Gruebele
Related What we have here is a hybrid of two molecules that are extremely sensitive to outside signals: sing... CHARLIE JOHNSON With what they're doing, you can go right down to the single-molecule level. CHARLES EDMONDS I tell my students to try to know molecules, so well that when they have some question involving mol... GEORGE WALD The problem is how do molecules react. Because if you want to transform a molecule into something us... WILLIAM LIPSCOMB If there is one single molecule in this universe running around loose, totally free of God’s sover... R.C. SPROUL We can track and see the production of single molecules, trace them and see how they assemble into s... ERIC BETZIG Many molecules are known that interfere with reading, or transcribing, genes' DNA to get RNA. But no... LIU JUN There’s as many atoms in a single molecule of your DNA as there are stars in the typical galaxy. W... NEIL DEGRASSE TYSON It's not very fun to do spectroscopy. GARIK ISRAELIAN The research included neutron resonance spectroscopy, the angular distribution of pion elastic and i... JAMES RAINWATER I think what really makes this telescope special is its high sensitivity, especially in spectroscopy... KLAUS PONTOPPIDAN Spectroscopy can probably answer the question, 'Is there anybody out there?' Are we alone? GARIK ISRAELIAN When air is hot, the molecules move fast and they have high kinetic energy. The colder the molecules... WOLFGANG KETTERLE According to the kinetic theory of gases, the mean kinetic energy of a molecule is a measure of abso... WILHELM WIEN When we did that, we found that putting a little nitrogen in these molecules explained the troubling... DOUG HUDGINS The nicotine molecule is too small to affect an immune response. By soaking it up, our carrier prote... HENRIK RASMUSSEN Climate change is a global issue - from the point of view of the Earth's climate, a molecule of ... JEFF GOODELL All of today's DNA, strung through all the cells of the earth, is simply an extension and elaboratio... LEWIS THOMAS There's a molecule inside of you that is connected to everything - every person, every energy, e... FOREST WHITAKER That is how we came to the idea of the molecule. AMIT AXELROD The immune system has evolved the capacity to react specifically with a very large number of foreign... BARUJ BENACERRAF The ear is so sensitive it can measure a vibration the width of the hydrogen molecule, and I'm watch... JOSEPH SMALDINO Calvin: Today for show and tell, I've brought a tiny miracle of nature: a single snowflake! I think ... BILL WATTERSON As long as the job growth continues, we'll continue to see rapid sales of new single-family homes an... CHARLES HEIMSATH I wondered whether the nuclear transfer techniques could be used to introduce purified macro-molecul... JOHN GURDON My own training is in the field of neuroendocrinology and I really became very fascinated many years... DEEPAK CHOPRA The animal world seizes its food in masses little and big, and often gorges itself with it, but the ... JOHN BURROUGHS The air molecules pass right through the rubber molecules, even without a puncture. People never kee... DONALD BACHMAN This is not a single technique, but really a research approach which takes the individual processes ... CARL STEEFEL The size compatibility between the detector and the detected species-DNA molecules in this case-make... ALEXANDER STAR The detailed geometry of the coenzyme molecule as a whole is fascinating in its complexity. DOROTHY HODGKIN After we knew the molecule, we knew that there was going to be intense litigation over it, DON CATLIN I have lived much of my life among molecules. They are good company. GEORGE WALD The laws of physics should allow us to arrange things molecule by molecule and even atom by atom, an... RALPH MERKLE This is the most serious single event in two years of trauma for energy consumers. ALLAN ASHER We believe that our application of terahertz technologies can provide a breakthrough in detection an... DAVID OLSON Because BCD galaxies are metal poor and very compact, the intense ultraviolet radiation from young s... YANLING WU You look at the floor and see the floor. I look at the floor and see molecules DAN AYKROYD Receptor chemistry, the chemistry of artificial receptor molecules, may be considered a generalized ... JEAN-MARIE LEHN In 2008, the Nobel Prize in Chemistry was awarded for work done on a molecule called green fluoresce... EDITH WIDDER Leonardo believed his research had the potential to convert millions to a more spiritual life. ... DAN BROWN They wanted to fire one X-ray photon at a hydrogen molecule, knock both electrons back, and the two ... WILLIAM MCCURDY Agarikon contains antiviral molecules new to science. Researchers for pharmaceutical companies may h... PAUL STAMETS The brain is not nourished on beans and truffles but rather the food manages to reconstitute the mol... ANTONIO GRAMSCI Our femtosecond snapshots can examine a molecule at discrete instants in time. AHMED ZEWAIL Typically, an historic site is considered by the National Park Service to contain a single historica... RICK RENZI These single-celled organisms are extremely sensitive to environmental changes. GERTA KELLER It's such a novel way of treating an addiction because it's not targeting any part of the brain. It'... DOROTHY K. HATSUKAMI The citation for the 1971 Nobel Prize in Chemistry reads, 'for contribution to the knowledge of ... GERHARD HERZBERG In order for life to have appeared spontaneously on Earth, there first had to be hundreds of million... WILLIAM PETER BLATTY You can't kill a prion.
Longest on air personality in US about the molecules of Mad Cow. HOWIE CHIZEK Different sorts of survival machine appear very varied on the outside and in their internal organs. ... RICHARD DAWKINS Chemists are getting very good at designing molecules. PAUL ANASTAS One of the outstanding problems in astronomy today is whether complex organic molecules of hydrogen ... YANLING WU An idea can be tested, whereas if you have no idea, nothing can be tested and you don't understa... JAMES D. WATSON We were pretty sure of its structure, but it wasn't a molecule that had ever been described before, DON CATLIN No. The answer was no, I was not all right. I nearly got knocked out. Knocked out by desire! Desire ... MEG CABOT (All the grief she had suffered over her lifetime had moulded her face into a mask of eternal sadnes... JEAN SASSON It turned out that the buckyball, the soccer ball, was something of a Rosetta stone of an infinite n... RICHARD SMALLEY My power is the ability to control water molecules and form them into ice. SHAWN ASHMORE But germs are the most common snowflake starters and lie at the heart of 85 percent of all flakes.2<... BOB BERMAN A composer is a guy who goes around forcing his will on unsuspecting air molecules, often with the a... FRANK ZAPPA The human self and the God self are both creations of molecules in the human brain. ABHIJIT NASKAR Carbon-carbon bond formation reactions are important processes in chemistry because they provide key... AKIRA SUZUKI The following general definition of an animal: a system of different organic molecules that have com... DENIS DIDEROT Telomerase Activation is the single most promising approach to reversing the effects of aging. MICHAEL FOSSEL The fact is, when men carry the same ideals in their hearts, nothing can isolate them - neither pris... FIDEL CASTRO Small molecules penetrate the tumor very efficiently, but are also removed very efficiently. Larger ... ASHUTOSH CHILKOTI To write our constitution is for the past, the present, and the future to come together all at once ... FERDINAND MARCOS This work made me more and more interested in biological matter, and I decided that I really wanted ... AARON KLUG We know what molecules are needed to sense light - what turns that signal that detects light into an... MARTIN CHALFIE I really think that effective acting has to do literally with the movement of molecules. GLENN CLOSE I really think that effective acting has to do literally with the movement of molecules. CHARLOTTE WHITTON We can?t see the difference between an asbestos molecule and a paper fiber under a light microscope,... DAVID FAWCETT New York is a granite beehive, where people jostle and whir like molecules in an overheated jar. Hou... NIGEL GOSLIN change the molecules, juices in the blood, so they do things differently. HAROLD CLURMAN At higher altitudes, there isn't enough air for ionized molecules to combine and become neutral agai... PROFESSOR UMRAN INAN No lens is quick enough to track the movement of the human body. The molecules are always moving. ROGER REES Every idea is endowed of itself with immortal life, like a human being. All created form, even that ... CHARLES BAUDELAIRE Time assumes another dimension now - work and absorption in the search for an answer. DANIEL KEYES After thousands of stretches, a pattern emerged. The molecule exhibited linear elasticity--a propert... PIOTR MARSZALEK Nanotechnology is the idea that we can create devices and machines all the way down to the nanometer... PAUL MCEUEN The human body is constantly undergoing a process of decay and of reconstruction. First builded into... ANNIE BESANT A wish is a single unit of hope. It’s a single request for something I dearly desire. SHARON WEIL As is known, the sugar molecule as it passes through lactic acid can easily be split by purely chemi... EDUARD BUCHNER The magnitude of the atomic weight determines the character of the element, just as the magnitude of... DMITRI MENDELEEV The recipe for a human doesn't fill up a shopping list as you may suspect. Just twenty-two eleme... KYLE HILL There's a joy in having the molecule of an idea, then testing it in front of audiences at secret... MIKE MYERS Sabrina: “But you don’t believe in marriage.” Linus: “Yes, I do. It’s why I’v... SAMUEL TAYLOR I know that, all my life, I've been going around in a fog. You're just a bunch of molecules until yo... CARY GRANT There is, in fact, no entity in the known universe that stores and processes information more effici... DISCOVERY INSTITUTE Studying organisms at a molecular level was totally compelling because it was moving from being a na... ELIZABETH BLACKBURN The smallest component of the human molecule is a vibration - the equivalent to a musical note. Taki... GARY HOPKINS It now seems certain that the amino acid sequence of any protein is determined by the sequence of ba... FRANCIS CRICK I will never use a substitute for butter. Margarine is one molecule away from eating plastic. If I... PAULA DEEN Earlier attempts to identify vaccine candidates resulted in only two molecules in a decade. EVANS TARACHA Progressive activists are angry that a Medicare-for-all single-payer approach was totally ignored du... BERNIE SANDERS The more the relationships of the nitrogen-rich substances to the cell nucleus were recognized, the ... ALBRECHT KOSSEL The absorption of the individual in the universal is only another term for its destruction. C. HAROLD DODD Our world isn't made of earth, air and water or even molecules and atoms; our world is made of l... TOM ROBBINS
More Martin Gruebele
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