That's really the tragedy, the amputations that could have been prevented with early aggressive treatment.

So many people are really needle shy. People are looking forward to being freed of insulin injections. This will be of great benefit to a significant number of diabetics, but not all diabetics.

Every treatment can potentially have an adverse effect. Everybody knows even two aspirins for a headache has a bad effect for someone somewhere. On balance, positive effects have to outweigh the negative.

I think the most exciting benefit is just the fact that we're now able to do a treatment that in the past has had quite a bit of toxicity for patients. It will result in increased dose intensity to the tumor, and fewer overall side effects for the patient.

Every minute counts in stroke. There is treatment for stroke, effective treatment, but this has to be administered urgently.

One thing we do for treatment is to assess those risk factors and minimize them.