The ancient dialogue between reason and the senses is almost always more interestingly and passionately resolved in favor of the senses.

One of the advantages of science is that one's work, ultimately, is either replicated or it is not.

Lithium remains the gold standard, but many drugs now treat bipolar disorder. Medication is critical and should be combined with psychotherapy. Compliance is a major problem. Patients believe that once they're better, they no longer need the medication. It doesn't work that way.

Because I teach and write about depression and bipolar illness, I am often asked what is the most important factor in treating bipolar disorder. My answer is competence. Empathy is important, but competence is essential.

Knowledge is marvelous, but wisdom is even better.

When public figures remain silent about depression, there is a cost to the rest of society. Silence contributes to the misperception that successful people do not get depressed, and it keeps the public from seeing that treatment allows many individuals to return to competitive professional lives.