The real risk factors are things like diet, smoking, obesity and high blood pressure. Hormone replacement therapy is a teeny-tiny risk. It makes no sense for someone who weighs 250 pounds and smokes to say she doesn't want to take HRT because it will give her a heart attack.

Dr. Lauren Streicher

Obesity Risk Smoking Therapy

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This should be reassuring for the woman who wants to take hormones for their intended purpose ? relief of hot flashes ? but is afraid of heart problems.

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