The regions of the brain we tend to use in our default state when we are young are very similar to the regions where plaques form in older people with Alzheimer's disease.

The default activity patterns of the brain may, over many years, augment a metabolic- or activity-dependent cascade that participates in Alzheimer's disease pathology. The regions of the brain we tend to use in our default state when we are young are very similar to the regions where plaques form in older people with Alzheimer's disease. This is quite a remarkable convergence that we did not expect.

We've been surprised to find out how malleable the brain is.

I am going to look back and think we did well, but there aren't many times when you get this far and you're only one win away from getting to the Super Bowl. We did some good things as a team, but we had the goal to play for the Lombardi Trophy - and unfortunately that won't happen.

Our feeling is that Brazil will default in the next year and you could have a similar problem to what you had in Argentina.

Young pitchers are going to be inconsistent. Young pitchers, when you expect really good things, you tend to get a little disappointed.