The role of money in politics is a major problem and particularly the role of unchecked anonymous money.

This is a problem. This is a major problem.

I'm going bald. I'm having a major problem with it.

I have one major problem with the Internet: It's full of liars.

I have one yardstick by which I test every major problem - and that yardstick is: Is it good for America?

some shelters don't take [pets], and that is really a major problem.