They have been there from the start and it will be really tough to lose the three of them. I know all coaches go through that, but it will be the first time for me.

They have really helped me to just improve myself as a coach. I have applied what I have learned and I can see it has had an impact on the girls' improvement.

We are hoping to at least win a game this year and see what happens from there. The girls have gotten a little better each year, all of them with at least 10-15 pin improvement. Some of them have improved by up to 30 pins from when they started.

We think this will provide more rapid development and approval of vaccines.

We are not saying we are confident these drugs will not cause liver toxicity,

The rule we will be publishing today represents the first major overhaul of the format and content or prescribing information in 25 years. With this step, the FDA believes we are driving into the information age, out of the 20th century and into the 21st century. These changes will not only enable better access to paper information but will enable the revolution in electronic prescribing information.