Using HPRD and several other databases, we have been able to develop a gold mine of new information for researchers seeking new ways of finding candidate genes involved in genetic diseases. And our demonstration that a protein's importance is not based on the number of interactions it has with other proteins is an important conceptual breakthrough. It eliminates a blind alley that could mislead researchers investigating the roles of specific proteins in the cell.
Akhilesh Pandey
Related Our demonstration that a proteins importance is not based on the number of interactions it has with ... AKHILESH PANDEY Genes are important because they are the blueprints for proteins, but proteins are where the action ... AKHILESH PANDEY Because of the relationship between programmed cell death and human disease, the identification of t... H. ROBERT HORVITZ Our paper has implications that are specific to this receptor, but many of the findings can be exten... CLAUDIO GROSMAN Genes are the blueprints for proteins, but proteins are where the action is in human life and health... AKHILESH PANDEY In the last few years these efforts have been remarkably successful. It has been possible to identif... DAVID BALTIMORE These proteins mimic known host proteins in the cell in a very interesting way. JACK DIXON Empathy is the new measurement of everything. It doesn't matter what religion you have, what God you... C. JOYBELL C. It's nice to be able to look at one protein, but life is driven by the interactions between prot... ERIC BETZIG This new facility is already producing thrilling data. For example, CBC scientists have been able to... BRENDA RUSSELL A DNA sequence for the genome of bacteriophage ΦX174 of approximately 5,375 nucleotides has been de... FREDERICK SANGER Several steps in the current test are difficult or inconclusive. You can imagine that with so many p... NICOLLE PACKER Several steps in the current test are difficult or inconclusive, ... You can imagine that with so ma... NICOLLE PACKER Importantly, such insights can now guide studies that focus on the normal function and interactions ... HUDA Y. ZOGHBI With these tools, we can study in detail how all the proteins are interacting with each other in rea... ALAN WAGGONER Growth factors are proteins that are involved in the development of nerve cells and are also importa... DORIT RON There are over 7,000 different types of proteins in typical eukaryotic cells; the total number depen... ADA YONATH [Several proteins have been identified as vital for bone growth, including one called BMP4.] We know... FRED KAPLAN The interactions we discovered in yeast could also help researchers select the human versions of the... JEF BOEKE And of course, identifying all human genes and proteins will have great medical significance. DANIEL NATHANS (All the grief she had suffered over her lifetime had moulded her face into a mask of eternal sadnes... JEAN SASSON They are functional mimics that work in the same way as proteins of the host cell, but they don't lo... JACK DIXON Proteins are constantly being degraded. Therefore, simultaneous production of proteins is required. ADA YONATH Mathematicians have been hiding and writing messages in the genetic code for a long time, but it'... CRAIG VENTER DNA is the master blueprint for life and constitutes the genetic material in all free-living organis... RICHARD J. ROBERTS Theoretical results suggest a small number of proteins may have the potential to give global coverag... BETTE KORBER We discovered a mechanism which is like the garbage machine of the body. We need to remove damaged p... AARON CIECHANOVER We began studying the molecules and proteins inside the nerve cell to find out whether this class of... HOWARD GENDELMAN You must save what you can of your life; you musn't lose it all simply because you've lost a part. HENRY JAMES We are pleased that the NOGA® System was able to play such an important role in exploring this new ... MARK MARTIN It is the most detailed study yet describing the interplay of proteins that occur in cells during he... AKHILESH PANDEY I think you can say that life is a system in which proteins and nucleic acids interact in ways that ... ANDREW H. KNOLL Until now we have not had a close-up view of the precise surface where the two proteins interact. Th... AMIT SHARMA Researchers are finding more evidence that diet early in life could play a role in the development o... KARIN MICHELS When you look at cells that don't yet have a specific function – aren't differentiated, compared t... SOPHIE LELIèVRE This 'foot in the door' mechanism of drug binding and action is a relatively new way of thinking abo... ANDREW MCCAMMON Genes are effectively one-dimensional. If you write down the sequence of A, C, G and T, that's k... FRANCIS COLLINS Wake up to a brand new day and realize why you woke up to meet the day! Live to the end of another d... ERNEST AGYEMANG YEBOAH It is a lie. ARTHUR MILLER [Dr. Ira Black, chairman of the neuroscience department at the Robert Wood Johnson Medical School in... IRA BLACK She was scarcely a year older than I was, dark-haired, slender, with a face that would break your he... GEORGE R.R. MARTIN A substantial part of the individual differences between the twins were due to new genetic effects b... HAROLD SNIEDER Our cells engage in protein production, and many of those proteins are enzymes responsible for the c... RANDY SCHEKMAN She wasn't bitter. She was sad, though. But it was a hopeful kind of sad. The kind of sad that just ... STEPHEN CHBOSKY So, I guess we are who we are for alot of reasons. And maybe we'll never know most of them. But even... STEPHEN CHBOSKY I love my mom so much. I don't care if that's corny to say. I think on my next birthday, I'm going t... STEPHEN CHBOSKY We Are All Infinite STEPHEN CHBOSKY You can't just sit there and put everyone's lives ahead of yours and think that counts as love. You ... STEPHEN CHBOSKY I saw other people there. Old men sitting alone. Young girls with blue eye shadow and awkward jaws. ... STEPHEN CHBOSKY That one moment when you know you are not a sad story. You are ALIVE. STEPHAN CHBOSKY Somos quienes somos por un montón de razones.Quizás nunca conozcamos la mayoría de ellas.Pero aun... STEPHEN CHBOSKY Ambos dijeron que tomara asiento y parecían hablar en serio, así que me senté. STEPHEN CHBOSKY I know these will all be stories some day, and our pictures will become old photographs. We all beco... STEPHEN CHBOSKY So I guess we are who we are for a lot of reasons. And maybewe'll never know most of them. STEPHEN CHBOSKY So I guess we are who we are for a lot of reasons. And maybe we'll never know most of them. STEPHEN CHBOSKY There's nothing like the deep breathes after laughing that hard. Nothing in the world like a sore st... STHEPHEN CHBOSKY no more pencils, no more books, no more teachers' dirty looks, when the teacher rings the bell, drop... STEPHEN CHBOSKY I don't know the significance of this, but I find it very interesting. STEPHEN CHBOSKY Maybe it’s sad that these are now memories. And maybe it’s not sad. STEPHEN CHBOSKY Oh happy day! A day to make a hay! And when it is mid-day, think about the day! And when you think a... ERNEST AGYEMANG YEBOAH It appeared to Harriet that she was always the one who remembered having seen other people. They nev... ELIZABETH TAYLOR All the proteins look very similar. Without the labeling, it would be like trying to find a specific... MANFRED AUER Brain cells are normally not sensitive to light. So by introducing light-sensitive proteins into spe... FENG ZHANG 35. God is entitled to a portion of our income—not because He needs it but because we need to give... JAMES C. DOBSON One of the major lessons in all of biochemistry, cell biology and molecular medicine is that when pr... JAMES ROTHMAN There are types of people who want to have leverage over other people's lives. For no other reason t... C. JOYBELL C. Through their work with fetal tissue, researchers hope to find ways to harness embryonic stem cells ... TOM ALLEN I like to open for a band as it brings on sort of a challenge and it makes things more interesting. ... KELLY JONES I am often asked how it is that I am able to value people to such a deep degree. Apparently, I exhib... C. JOYBELL C. You're showing a new part of biology that was completely unknown. Future drugs might work more effec... CLAES WAHLESTEDT You release the pain of the past and press on. It's a new day, and God is doing a new thing. He want... CRAIG GROESCHEL Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to ge... SAM KEAN In the late 1970s, when I was a professor at Caltech, I pioneered four instruments for analyzing gen... LEROY HOOD Life is not a game. Still, in this life, we choose the games we live to play. J.R. RIM What is the Other?" they ask. The Other is the one who taught me whatI should be like, but not ... PAULO COELHO Aging is not currently regarded as a disease, but researchers tend increasingly to view it as the co... MARíA BLASCO MARHUENDA I realized that day that blessings come in a variety of shapes, colors, and sizes. CRAIG GROESCHEL Valkyrie stood there and waited for her to start making sense. "There is a vegetable-plant hybr... DEREK LANDY It was thought collagen was a relatively recent invention in vertebrate evolution that unites us wit... MARTIN COHN I wish I was home", She said miserably. She tried so hard to be brave, to be fierce as a... GEORGE R.R. MARTIN My goals over the decade include to develop new drugs to treat intractable diseases by using iPS cel... SHINYA YAMANAKA You're still lovely," Mor said a bit gently. Elain offered a half smile. "I suppose that war m... SARAH J. MAAS A virus is not just DNA; a virus is also packaged up, covered over with a series of proteins in a ni... FRANCIS COLLINS We see the potential for a production vehicle with tremendous flexibility, which is a real alternati... LEENDERT STAAL We are excited about this discovery because it provides a genetic test that will lead to improved pa... LAURA RANUM Lithium regulates the proteins that control the body’s inner clock. This clock runs, oddly, on DNA... SAM KEAN I was very grateful to have heard it again. Because I guess we all forget sometimes. And I think eve... STEPHEN CHBOSKY I guess we are who we are for a lot of reasons. And maybe we'll never know most of them. But even if... STEPHEN CHBOSKY Fertilization is a very basic cell interaction, a very important medical, economic and social intera... ANDREW SINGSON It was thought collagen was a relatively recent invention in vertebrate evolution that unites us wit... MARTIN COHN My mission at Google is to develop natural language understanding with a team and in collaboration w... RAY KURZWEIL We try to educate people people on what's inside our products. A lot of people choose a supplement b... KYLE LOVE It is not easy for me to digest meat. I waste too much energy in digesting meat, and that's why ... ILYA ILYIN Love is blind, and a deaf-mute too. PATRICK ROTHFUSS This process is highly dependent on the fact that the functions of promiscuous proteins can be alter... JAY KEASLING Such understanding is required for researchers to develop new and much-needed approaches to prevent,... DAVID ALTSHULER The magnificence of such objects hardly pertains to the human. They live only in a world of icons an... ANGELA CARTER The development of methods to monitor protein dynamics in cells together with the discovery of speci... AARON CIECHANOVER You deserve to be with somebody, who knows you're the one, from that very first moment he lays eyes ... C. JOYBELL C. Each man lives in his own universe and when he dies the world is over BANGAMBIKI HABYARIMANA
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