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We now know with certainty that Aspirin is effective in both men and women in reducing cardiovascular events.

Dr. Jeffrey Berger

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While our analysis showed that aspirin may have different effects in men and women, the relatively small number of heart attacks among women and strokes among men suggest that more research is needed to better understand any differences in cardiovascular response to aspirin.
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That basically sets up a chain of events that will allow a blood clot to form near the hole or in it and then be pushed into the brain by the prime minister's own heart beat.
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