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What we are talking about is still-fertile women, finished with having children, who have some event that leads to surgery to remove their uterus, and the surgeon removes one or both ovaries to prevent cancer.

Walter Rocca

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What we showed is that for the surgery to be a risk factor, it has to be done before menopause. If before age 46 you remove two ovaries, you get a 70 percent increased risk of dementia. And we discovered that women who have only one ovary removed before age 38 -- this is a surgery more often done in younger women -- we see a 260 percent increase in dementia. That is quite a dramatic and somewhat unexpected finding.
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