Your 40s are a major trough. About the age of 50, feelings of satisfaction begin to rebound and keep rising into your 50s, 60s and 70s, with health being a major factor.

I'm sorry, but I can't imagine being an American icon! It would be pretty difficult to look at your face in the mirror and think of yourself as that without laughing and spitting toothpaste all over!

About the time I turned 50, I experienced the profound biological change that often accompanies women at that age. Also, I put two kids in college and lost both of my parents, so I'm no longer somebody's daughter.

Twins are a high-risk pregnancy, by definition. The quieter I am, the longer I can keep them growing.

A diagnosis is burden enough without being burdened by secrecy and shame.

I've always had a lot of ambivalence about fame and celebrity.