Importantly, virtually all of this risk can be captured by looking at a single-letter change in DNA - ideal for the development of a genetic test for assessing individual risk and developing more personalized and effective prevention strategies. This is also an exciting starting point for the discovery of new drugs, and we are actively pursuing the development of both diagnostic and therapeutic products to better prevent and treat type 2 diabetes.
Kari Stefansson
Related This discovery sheds new light on the biological causes of the disease. Importantly, virtually all o... KARI STEFANSSON I like to open for a band as it brings on sort of a challenge and it makes things more interesting. ... KELLY JONES (All the grief she had suffered over her lifetime had moulded her face into a mask of eternal sadnes... JEAN SASSON History is a wheel, for the nature of man is fundamentally unchanging. What has happened before will... GEORGE R.R. MARTIN Empathy is the new measurement of everything. It doesn't matter what religion you have, what God you... C. JOYBELL C. You're still lovely," Mor said a bit gently. Elain offered a half smile. "I suppose that war m... SARAH J. MAAS We are excited about this discovery because it provides a genetic test that will lead to improved pa... LAURA RANUM Use of this information to select and treat the patients at highest risk for progression earlier may... KATHY ORDONEZ The issue isn't whether he loved you, it's how much. Too much. Love can be poison SARAH J. MAAS I am broken and healing, but every piece of my heart belong to you. SARAH J. MAAS He thinks he'll be remembered as the villain in the story. But I forgot to tell him that the villain... SARAH J. MAAS Night gathers, and now my watch begins. It shall not end until my death. I shall take no wife, hold ... GEORGE R.R. MARTIN Hodor," said Hodor. GEORGE R.R. MARTIN You do what you love, what you need SARAH J. MAAS I turned. Rhysand leaned against the archway into the sitting room, arms crossed, wings nowhere... SARAH J. MAAS It's important to remember we're talking about giving drugs with significant side effects to healthy... FRAN VISCO Not," Swift said firmly, "for all the tea in China." "That expression has never made sense to m... LISA KLEYPAS Each man lives in his own universe and when he dies the world is over BANGAMBIKI HABYARIMANA This is an exciting new area with potential for opening new therapeutic avenues for diseases that ar... JOEL WEINSTOCK I'm always highly irritated by people who imply that writing fiction is an escape from reality. It i... FLANNERY O'CONNOR Hard to restrain, unstable is this mind; it flits wherever it lists. Good it is to control the mind.... GAUTAMA BUDDHA We have been informed of this by both parties. It's a welcome development, and we'll be looking for ... PJ CROWLEY Each day before the end of eve she sought her lover, nor would him leave, until the stars ... J.R.R. TOLKIEN Absoballylutely top hole, wot. A and B the C of D I'd say. . . Above and Beyond the Call of Duty. BRIAN JACQUES Our risk management strategy has been to better understand our own products and marketsnow and in ... EUGENE KIERNAN A more nutritious diet and moderate exercise reduce the risk of developing adult diabetes by 58 perc... TOMMY THOMPSON A common gene variant conferring elevated risk of (type 2 diabetes) has been earnestly sought by the... KARI STEFANSSON She made a fence of phrases, which seemed a treachery to herself. ELIZABETH TAYLOR You are the blood of the dragon. You can make a hat. GEORGE R.R. MARTIN When we understand more about the genes and the environmental factors that influence someone's risk,... ALISON GOATE When we understand more about the genes and the environmental factors that influence someone's risk,... ALISON M. GOATE This software captures all the details of what their needs are. It's really the starting point of th... JOHN WILLIAMS Pastor Smith did not have the religious constitution needed to provide salvation for any of us who�... CHERYL R COWTAN And what good is a voice when so few will listen? STACEY JAY If God give you strength and courage, don't use it to intimidate people or overpower them, rather us... ANTHONY LICCIONE Our study further defines melanoma risk in post-menopausal women and, it is hoped, will sensitize th... CAROL ROSENBERG Our study further defines melanoma risk in post-menopausal women and, it is hoped, will sensitize th... CAROL A. ROSENBERG You know something is wrong when you are known for what you are against, instead of what you are for... JADE HAJJ I want to share this bed with you, though," I breathed. "I want you to hold me." Stars flicker... SARAH J. MAAS It's surprising to see such a significant change within such a short time-period. This is the first ... JOYCE LEE Both drugs lower the risk of developing breast cancer by 50%. DR. LORA WEISELBERG Fiber has been associated with a lower risk of diseases such as Type II diabetes and obesity. By inc... LISA MCDERMOTT She was scarcely a year older than I was, dark-haired, slender, with a face that would break your he... GEORGE R.R. MARTIN Ses’ach L’ru!” Came the slightly muffled chorus. This was Ruminarii for ‘Hail the Captain.�... CHRISTINA ENGELA God created us in his image, male and female, with personhood and sexual passions, so that when he c... JOHN PIPER Who are we if not the stories we pass down? What happens when there's no one left to tell those stor... CARRIE RYAN Anger - a beast within us that needs taming. SARU SINGHAL Iran is actively pursuing the development of weapons of mass destruction and ballistic missiles. HOWARD BERMAN From the Kindle Book Reflections in the Mirror of Life: “In a slum somewhere in India As... THE PROPHET OF LIFE I frowned at the eye in my palm. "What, literally shout at the tattoo?" "You could try rubbing ... SARAH J. MAAS What makes this a much longer process in the U.S. is the FTC is looking not only at products on the ... COREY DAVIS The prospect of finding a safe and effective new approach to both prevention and treatment of Alzhei... GREGORY COLE The hope is we will one day be able to identify the highest-risk groups and intervene early to preve... ALLAN REISS I was not a pet, not a doll, not an animal. I was a survivor, and I was strong. I would no... SARAH J. MAAS I sipped from my wine. "And if he had grabbed me?" There was nothing but uncompromising w... SARAH J. MAAS There you are. I've been looking for you. His first words to me— not a lie at a... SARAH J. MAAS I was not prey any longer, I decided as I eased up to that door. And I was not a mouse. I ... SARAH J. MAAS No one was my master— but I might be master of everything, if I wished. If I dared. SARAH J. MAAS He drained his glass. "I made a mistake." "It's not the end of the world if you do that every n... SARAH J. MAAS I will kill anyone who harms you," Rhys snarled. "I will kill them, and take a damn long time doing ... SARAH J. MAAS Julia poured tea gracefully, but it all ran over into the saucers. ELIZABETH TAYLOR The next day, the villages came closer together until the beginnings and endings could no longer be ... PATRICK W. CARR It appeared to Harriet that she was always the one who remembered having seen other people. They nev... ELIZABETH TAYLOR Would you like me to grovel with gratitude for bringing me here, High Lord?" "Ah. The Suriel to... SARAH J. MAAS If in barbed wire things can bloom, why couldn't I? I will not die, I will not die. FRIEDL AND THE CHILDREN OF TEREZIN At the end of the warehouse was a dais constructed from pallets of books: stack of vampire novels, w... RICK RIORDAN Working with Wal-Mart and SAM'S CLUB allows us to directly reach large populations affected by diabe... MARY AUSTIN Aesthetic matters are fundamental for the harmonious development of both society and the individual. FRIEDRICH SCHILLER The new BNF for Children is a very exciting development and an important tool in improving the quali... JANE KENNEDY May I never neither turn left nor turn right in my journey of life, but may I go straight to Christ ... ERNEST AGYEMANG YEBOAH Swift as a deer. Quiet as a shadow. Fear cuts deeper than swords. Quick as a snake. Calm as still wa... GEORGE R.R. MARTIN You know nothing, Jon Snow. GEORGE R.R. MARTIN All ways of living can be sanctified, and for each individual, the ideal way is that to which our Lo... PIERRE TEILHARD DE CHARDIN step by step; the language of orderliness. ERNEST AGYEMANG YEBOAH This is where we have the design and development of the best submarines in the world, ... That is wh... ROB SIMMONS When each and every believer rises up to serve others and function according to their capacity, the ... HENRY HON The opportunity is to lower the cost of these drugs. The risk is that state Medicaid programs use th... JOHN GOODMAN We're very concerned that the ultimate result will be disease substitution instead of disease preven... BARBARA BRENNER We have tears in our eyes As we wave our goodbyes, We so loved being with you, we three. ROALD DAHL The fear of God is the only cure for the fear of people. CRAIG GROESCHEL Clay in the hands of a good potter suffers so many good turns, but in the end, we see its real and t... ERNEST AGYEMANG YEBOAH I feel so honored to be able to say "What I do is for my son" without that being an excuse to do stu... C. JOYBELL C. We pay a price for everything we get or take in this world; and although ambitions are well worth ha... L.M. MONTGOMERY In the journey of life, certain paths may seem to be leading nowhere because of a mountain or hill o... ERNEST AGYEMANG YEBOAH We die a day at a time BANGAMBIKI HABYARIMANA Your life is the proof that you have a purpose You are the treasure that you are searching for MIMI NOVIC Science is publishing this study because it provides information necessary for developing drugs and ... DONALD KENNEDY You must save what you can of your life; you musn't lose it all simply because you've lost a part. HENRY JAMES I wish I was home", She said miserably. She tried so hard to be brave, to be fierce as a... GEORGE R.R. MARTIN Anything man can make, man can destroy. JONATHAN ANTHONY BURKETT Even though he was inside the house, I could still hear Vlad’s sardonic mutter of “Where’s a t... JEANIENE FROST We're looking at the development of genetic tests which are easy and robust with a quick turnaround. CHARLES YATES In my dreams, I see 10 to 20 years from now, people who are 50 to 55 years old will get a cognitive ... ANNE FAGAN NIVEN That boy had wanted to be Ser Arthur Dayne, but someplace along the way he had become the Smiling Kn... GEORGE R.R. MARTIN Selfish people look for success and are in great majority with good bonhomie, but others who crave f... ANUJ SOMANY An Indigo Bunting let out a trill, a cheery song, reminding me of better days, of hope and happiness... CHERYL R COWTAN While Maddox now believed the demon did not want to hurt Ashlyn, he wasn't willing to take a chance.... GENA SHOWALTER Your life today is the result of a series of decisions you made that have caused you to arrive where... CHRIS PRENTISS A strong personal philosophy does more than sustain us through the tragedies of life. It also stains... CHRIS PRENTISS The answers are never "out there." All the answers are "in there," inside you, waiting to be discove... CHRIS PRENTISS
More Kari Stefansson
A common gene variant conferring elevated risk of (type 2 diabetes) has been earnestly sought by the... KARI STEFANSSON African-Americans who have this variant are almost certain to develop heart attacks. If you remove t... KARI STEFANSSON It is a disease that occurs at the interface of genes and environment. KARI STEFANSSON This has turned out to be the disease that has been the most difficult for geneticists to crack, pro... KARI STEFANSSON This discovery sheds new light on the biological causes of the disease. Importantly, virtually all o... KARI STEFANSSON This discovery sheds new light on the biological causes of the disease. KARI STEFANSSON It's funny that on a little rock in the North Atlantic we found a gene variant that has so much impa... KARI STEFANSSON If this drug makes it to the market, it is bound to become a blockbuster. KARI STEFANSSON African Americans with the variant come very close to facing certainty of having a heart attack. KARI STEFANSSON The philosophers of the Middle Ages demonstrated both that the Earth did not exist and also that it ... VILHJALMUR STEFANSSON What is the difference between unethical and ethical advertising? Unethical advertising uses falseho... VILHJALMUR STEFANSSON Molti preferiscono tacere quando la vita fa più male, spesso le parole sono solo pietre inerti, ves... STEFANSSON JON KALMAN I'm the queen of the independent video! KARI WUHRER My body is my greatest asset. KARI WUHRER I wanna create a character that's really memorable... like Julia Roberts did in 'Pretty Woma... KARI WUHRER The people that are fans of animation are really the people that are keeping the art form of animati... KARI WAHLGREN I always knew that I wanted to do voiceovers as part of my career. I just kind of didn't expect ... KARI WAHLGREN I love cartoons, I love comic books and graphic novels. 'Batman: The Animated Series' was a ... KARI WAHLGREN I'm a huge Wonder Woman fan - I have about 12 coffee mugs at home! KARI WAHLGREN Somebody took something that belonged to us, that we had taken care of. That's the frustrating part. KARI AUSTIN They do make really good pets just because they're affectionate and playful and they honestly don't ... KARI AUSTIN We put bells on them, we're putting up another fence and doing more for security. KARI AUSTIN We don't like to think of anyone eating them, but we know that happens. KARI AUSTIN They were our pets. Whoever did this went to a lot of trouble to steal someone's pets. KARI AUSTIN I think the entire state of Maryland and D.C. within the next two years will be smoke-free. KARI APPLER We know the public is wildly enthusiastic about both. KARI APPLER Momentum is building for smoke-free measures around the region. It's just a matter of time before th... KARI APPLER It's a good time of year. Legislation is at the forefront of people's minds. KARI APPLER It's definitely encouraging. I'm fairly certain that the majority of state legislators would support... KARI APPLER Now, if you can get 25 percent guys in a class, you're doing great. I think it's because there are s... KARI ANDERSON I just fell in love with it. KARI ANDERSON There was very big pressure for me to be very thin, because I was very tall. I was so lonely for my ... KARI ANDERSON Sometimes people can be a little fickle. They'll go for the newest, hottest thing. KARI ANDERSON Those gains resulted from the acquisition of several companies, held in our portfolio of venture cap... ROSS KARI The bulk of these charges, in fact, are reductions of the non-cash venture capital gains recognized ... ROSS KARI Venture capital investing is a volatile business, but over the long term it has earned very attracti... ROSS KARI Think of it more as a supply chain preservation instead of a gizmo here or a gizmo there. KARI FLUEGEL Sometimes they have all five players out and no one in the paint and they send cutters through. It's... KARI WILLIAMS If only I could step back into the time of old movies, if only I could be given the opportunity to d... KARI MATCHETT Want my spend, Precious?" Shane shuddered, the pleasure from his ass streaking to his balls and then... KARI GREGG It's another week for me to wear this Missouri State uniform. I like playing for this coaching staff... KARI KOCH Given how glorious Oregon is, if we're ranked in the middle and (are) one of the most wonderful stat... KARI WESTLUND It's a gorgeous plant, host to butterflies. KARI RUDER Loving honesty builds one up, bitter honesty makes one strong, whereas secrets, even those kept with... KARI TORKELSON We have a problem of debris on our beaches and . . . our Beach Sweeps results are evidence of that p... KARI JERMANSEN There weren't many tough ones in the first period when I didn't feel that comfortable. In the second... KARI LEHTONEN Without the good fundamental news, it's going to be difficult to call the rally a sustainable rally. KARI BAYER Markets got a little ahead of themselves. It's not much of a pull back (Tuesday) after such a big ga... KARI BAYER We recommend investors sell into strength because of the uncertainties lurking. KARI BAYER We are concerned that someone would believe these false accusations. You certainly want people in th... KARI BJORHUS At the time, we thought individual meetings [with individual schools] would be more helpful, because... KARI BJORHUS It is a very unfortunate. The actual volume in terms of sales is small but it is the larger issue of... KARI BJORHUS The University of Michigan is an important school, and I respect the way they worked with us on this... KARI BJORHUS It is an amazing vehicle. Even with some of the equipment being older, the things we can do with tha... KARI FLUEGEL This is not flight hardware. This is ground support hardware, not the gadgets and gizmos that are ac... KARI FLUEGEL The shuttle is still on the cutting edge. KARI FLUEGEL The main thing that I would like to make clear is that we are not purchasing equipment over the Inte... KARI FLUEGEL The response to the 'Casablanca' theme, casino games and the new location has been extremely positiv... KARI CORDLE It's a way of locking in the progress we've made in ocean protection in the last 20-plus years. KARI JERMANSEN It's some of our first shooters' time in the outdoors, we are going to use this tournament for exper... KARI GRANVILLE Lindsay is very dedicated and does everything she needs to do to be in the top of the field. KARI GRANVILLE It will be something nice to look back on later, but I don't really think about awards too much righ... KARI KOCH It was two good wins here, but a lot of other teams are playing confident. We just have to carry our... KARI KOCH It went excellent. I'm not lying. I said I didn't want to come here because of that speech. I saw Ja... KARI KOCH This is definitely going to shock some people. Maybe it will put a little fear in them. KARI KOCH We only needed a two, so I wasn't really looking for the 3. I just did the wrong thing. KARI KOCH We were up by eight, but we've been down by eight in that same situation. You have to know that a te... KARI KOCH I'm sure they would have been key for us. They are both learning every day by watching and that's a ... KARI KOCH They knocked us off last year so you definitely have that deep down and still think about it. We als... KARI KOCH There's other people that can (score) so that's a great thing. I wasn't doing it tonight and other p... KARI KOCH I just let myself get frustrated and that's the first time I've done that this year. Hopefully it's ... KARI KOCH I told you not to judge a book by its cover. KARI KRUGER They just think it's fun. KARI KRUGER They seem to like it. They like that they're the first to see their book. KARI KRUGER I was just sliding around, swimming and hoping I was going to hit it and it went under my pad. KARI LEHTONEN We are making some bad mistakes and I am letting some easy goals in. KARI LEHTONEN We will now use the Olympic break as a part of my rehab program. KARI LEHTONEN I didn't have any pain at all. A couple of goals I wasn't very happy about. It feels bad because we ... KARI LEHTONEN I'm very disappointed that I'm unable to represent my country, but after speaking with our doctors, ... KARI LEHTONEN I had hoped to be further along with my groin injury and strong enough to help Finland compete for a... KARI LEHTONEN It was definitely the hardest decision of my life. I'm very disappointed. KARI LEHTONEN It's the only thing I can do right now. I don't want to go over there and hurt myself. It would be a... KARI LEHTONEN It's definitely the hardest decision of my life. But I had to face facts. I can't handle 10 games in... KARI LEHTONEN Teachers said they were able to open up whole new discussions just by doing this project. KARI LYLES It's a great thing that the company does this and it's a great time to remember them. We often remem... KARI LYLES I tried to get as many administrators and principals as possible and sent out 20 to 25 e-mails. The ... KARI LYLES This year, the kids did their own project. Some bring tears to your eyes. KARI LYLES It started because of a colleague of Bill's from Texas. What they did was adopt a unit in Iraq and l... KARI LYLES Hopefully a lot has changed since Murphy Brown . And we are doing a sitcom here. But it seems like t... KARI LIZER The odds are always stacked against you. KARI LIZER That part is not based on my life. That's just my nightmare, but I'm divorced. I have kids. My kids ... KARI LIZER It's a great deal for individual investors, but I don't know what kind of incentive the elimination ... KARI PINKERNELL Many fund managers, if they're not in for a two-day rally, they risk falling behind for the whole ye... KARI PINKERNELL You do not want to try to time these short-term rallies. The market is trading on propaganda, not fu... KARI PINKERNELL They don't want give out a dividend because they think they'll give up their growth stock status. Bu... KARI PINKERNELL You can't expect everyone to stay on. But today, everyone stayed on the beam. That's happened only o... KARI RIENDEAU Our girls all had a fantastic meet. We stuck everything. It was our best performance this year. Ever... KARI RIENDEAU We had some falls in the East Region meet, so I think we can still have some better scores. We have ... KARI RIENDEAU It was hard. I was very nervous about the season at the beginning. But everything has progressed. We... KARI RIENDEAU Having her helps very much. She is pretty strong in every event and she is a good pep-talker, too. KARI RIENDEAU It was a small meet. But I think the girls did pretty well. KARI RIENDEAU Emily Wong had another good meet. KARI RIENDEAU We are committed to getting those dollars to our partners. KARI RIDDER Committed volunteers are the backbone of our organization. Lives are changed in this community becau... KARI RIDDER It's a great feeling that we can do the things we set out to do. KARI RIDDER We're going to be a better hitting team than passing team. Our setters are going to be good leaders ... KARI ROSENBERG We took a lot of hits to graduation, but we'll be strong again. We'll be in the mix in the conferenc... KARI ROSENBERG She's shows good understanding of how to direct her hits. And she passes the ball well. KARI ROSENBERG She's shown a lot of improvement. She's able to direct and hit a variety of serves and she's showing... KARI ROSENBERG What we're delivering is more than just hardware. We're trying to get three industries to work toget... KARI SKOOG Intel's Digital Home Fund supports initiatives in the digital home space to help people enjoy and ac... KARI SKOOG The vision is to enable customers to have access to their content, both personal ? photos, home vide... KARI SKOOG There is such a demand for native plants in this area. People will travel to South Florida to find s... KARI RUDER I'm sure that the marathon is having an impact. They typically bring about 1,500 room nights for the... KARI SLIVA Winter is typically our slowest tourism season, so to have this caliber of event occur during the of... KARI SLIVA The game's economic impact is quite significant. It's probably about three-quarters of what we would... KARI SLIVA Hosting an NCAA Division I tournament is huge and we consider it an honor to host such a prestigious... KARI SLIVA If you see a deal, you need to lock it in. KARI SWARTZ It's fall, it's pre-holiday craziness and it's a great way for you to go out with your girlfriends o... KARI SWARTZ If it's a short trip to go see your grandma in Minneapolis, that's something where you can kind of w... KARI SWARTZ Check in with your friendly convention and visitors associations. There are many ways to see Oregon ... KARI WESTLUND American workers receive the least amount of vacation days (12 on average) among all the countries t... KARI SWARTZ Dana was our fire. She really toed the line. KARI WILLIAMS That's always been my policy. Freshmen play freshman basketball. Now (freshmen) come from three diff... KARI WILLIAMS It was a good finish for us. We didn't have trouble with the press and still did a lot of scoring af... KARI WILLIAMS We weren't getting back on defense, we weren't moving on defense. And for the most part, we couldn't... KARI WILLIAMS I'm really, really happy with the way we distributed the ball. We got everyone some scoring tonight. KARI WILLIAMS We definitely want to bring our game, home or away. I've told the girls this is going to be our test... KARI WILLIAMS I think the first half was incredible. We didn't even score as much as we could have. We passed arou... KARI WILLIAMS It was a really good game, a pretty rough game. Free throw shooting really was the only difficult pa... KARI WILLIAMS She played her typical game, just really good aggressive defense, outstanding on the boards, diving ... KARI WILLIAMS She's on the court for her defense. When you're not making shots, it's hard to shoot. But she's a de... KARI WILLIAMS It's either a freeing experience thing for me or it's some kind of insecurity thing where I really l... KARI WUHRER Kirjailijan ammatissa parasta on se, ettei tapaa uusia ihmisiä. KARI HOTAKAINEN To whom are you for? Is a good question to ask. For one way sows to life, The other... KARI L. GREENAWAY "Success is a simple formula do your best and people may like it."
pressure cleaning palm beach KARI L LAMBERT