This discovery sheds new light on the biological causes of the disease. Importantly, virtually all of this risk can be captured by looking at a single-letter change in DNA -- ideal for the development of a genetic test for assessing individual risk and developing more personalized and effective prevention strategies.

This discovery sheds new light on the biological causes of the disease.

This has turned out to be the disease that has been the most difficult for geneticists to crack, probably because of the large environmental contribution.

It is a disease that occurs at the interface of genes and environment.

Importantly, virtually all of this risk can be captured by looking at a single-letter change in DNA - ideal for the development of a genetic test for assessing individual risk and developing more personalized and effective prevention strategies. This is also an exciting starting point for the discovery of new drugs, and we are actively pursuing the development of both diagnostic and therapeutic products to better prevent and treat type 2 diabetes.

A common gene variant conferring elevated risk of (type 2 diabetes) has been earnestly sought by the genetics community for many years.