Penny: I feel just like Mother Teresa. Except for the virgin part. That ship sailed a long time ago.

When I started on 'Big Bang,' I was the only girl; I felt like I had four brothers. Then Melissa Rauch and Mayim Bialik came on the show, and we got really close. Because of that, I'm not so quick to judge other women, and now I have all these amazing new girlfriends.

The predominant theory of the origin of the universe is the Big Bang.

I bleed feminism. I get equal pay to my male costars on a big show; I have my own home. I'm as independent as you could possibly be.

Oh gravity, thou art a heartless bitch.

James Garner was a gift to our business and an example of honesty and pure class. It was an honor to have worked beside him and receive his bear hugs every day.