When I started on 'Big Bang,' I was the only girl; I felt like I had four brothers. Then Melissa Rauch and Mayim Bialik came on the show, and we got really close. Because of that, I'm not so quick to judge other women, and now I have all these amazing new girlfriends.

Penny: I feel just like Mother Teresa. Except for the virgin part. That ship sailed a long time ago.

The predominant theory of the origin of the universe is the Big Bang.

Tune your television to any channel it doesn't receive and about 1 percent of the dancing static you see is accounted for by this ancient remnant of the Big Bang. The next time you complain that there is nothing on, remember that you can always watch the birth of the universe.

'Big Bang Theory' is not my kind of show. It's not my humor. I don't like multicam comedies. I don't want an audience to tell me when to laugh.

If the Big Bang is true, that means everything that came out of it, all of the particles, all of us, there is a scientific force that connects it all that we don't really know about.