We are very excited that this simple and inexpensive therapy turned out to be so effective and well-tolerated in patients with CF. It is especially gratifying to see patients in our own clinical practice embrace and benefit from it.

Surfers with cystic fibrosis had fewer lung exacerbations.

This is the recommended therapy for all patients. We get 100 percent of our patients on it.

Electroconvulsive therapy is not considered for garden-variety depression. If it's more refractory, if other treatments have failed or it's suicidal depression, and you don't have time to wait around to see if a medication is going to work, it's considered the gold standard of treatment.

This is the way we're going for patients with HIV (who are) starting therapy for the first time. It's becoming very easy and safe and effective.

There is no reason to use the combination therapy for primary prevention, whereas it might be useful in patients who have already had a heart attack or stroke.