We believe that such a significant increase in longevity is due to the protective effect against cancer produced by caloric restriction - incidences fall by 40 percent if we compare them with the mice that produce more telomerase and have a normal diet - and, added to the presence of longer telomeres, this makes the mice live longer and better.
María Blasco Marhuenda
Related We see that mice that undergo caloric restriction show a lower telomere shortening rate than those f... MARíA BLASCO MARHUENDA Normal levels of telomerase didn't lengthen short telomeres in our mice, so the longer the telomeres... CAROL GREIDER I like to open for a band as it brings on sort of a challenge and it makes things more interesting. ... KELLY JONES This enzyme, called telomerase, slows the rate at which telomeres degrade, and research indicates th... ELIZABETH BLACKBURN If you put animals on a 30- or 40-percent calorie-restricted diet, they live 30 to 40 percent longer... DR. LUIGI FONTANA Why do we have these silly experts bemoaning the fact that we're living longer? ... As I live longer... STEVE FORBES If you were to search for the genetic mutation behind this mouse's disease, you wouldn't find it; th... CAROL GREIDER Work by Maria Blasco, Calvin Harley, Michael Fossel, Woodring Wright and Shay and Ronald Depinho in ... LIZ PARRISH But that is no longer the case after such a prolonged and significant increase. JASON WONG Evidence from controlled clinical trials such as this is crucial for understanding caloric restricti... EVAN HADLEY The answer isn't more time but a greater awareness of the time we have. CRAIG GROESCHEL Empathy is the new measurement of everything. It doesn't matter what religion you have, what God you... C. JOYBELL C. Now is the only time we have, and the only time that we have any control over. RICHARD CARLSON Convinced that we're living the whole time that we're dying. We decide to go out walking the wh... TEGAN QUIN We know that more people will live longer in retirement, but also that more retirees will have longe... DAN HOUSTON The Biggest Threat to our Democracy, Freedoms and Future is Leadership that fosters and Appeases the... MICHAEL HARRIS And the MICE industry constituted 5 per cent, or RM1.5 billion, of that total. That calculation is e... ANTHONY WONG We sang the song as children of the mystery that we hoped to one day comprehend and now, at last, we... MISHI MCCOY I agree Maria Blasco has achieved amazing things with telomerase induction and we are hopeful this w... LIZ PARRISH Each of us views life through a different lens. What we think is colored by the baggage we carry, an... LAURIE BUCHANAN, PHD Now is the only time we have, and the only time we have any control over. RICHARD CARLSON We believe that nanotechnology will have a transformative effect on cancer diagnosis and treatment. ... ANDREW ESCHENBACH We believe that nanotechnology will have a transformative effect on cancer diagnosis and treatment. ... ANDREW VON ESCHENBACH We should not blame people by the mistakes of others. DANIEL MELGAçO See the world as it is, not as you wish it would be E. LOCKHART Food Allergies Are Not Due to Food, Rather Are Due to the Constant Contamination of That Food That Y... THEHEALTHFOODGURU We observed that women in the low-fat diet group had a 9 percent lower risk of breast cancer than th... DR. ROSS PRENTICE We have tears in our eyes As we wave our goodbyes, We so loved being with you, we three. ROALD DAHL We can reduce these cancer rates - breast cancer, prostate cancer, colon cancer - by 90 percent or m... JOEL FUHRMAN While any increase is difficult for our citizens, we successfully reduced the increase by 40 percent... ATTORNEY GENERAL GREG STUMBO Our estimates suggest that a tax increase of 1 percent of GDP reduces output over the next three yea... CHRISTINA ROMER We still face a longer-range deficit problem and that will be exacerbated by increases in Medicare a... LYLE GRAMLEY Truth is irrelevant. What is relevant is whether or not they believe it." The logic in th... SARAH MACLEAN Want LESS! Need LESS! Live MORE! TANYA MASSE We hope to make a difference in setting a challenge goal for the nation of eliminating suffering and... BEA FUENTES Wake up to a brand new day and realize why you woke up to meet the day! Live to the end of another d... ERNEST AGYEMANG YEBOAH That's why we seize the moment try to freeze it and own it, squeeze it and hold it. EMINEM Use your heart. Understand. Learn to see things in the now, not as they were or will be, or as ... E.J. PATTEN Life is a competition to eliminate fear and doubts to double our life to live better not bitter in t... NAZIM AMBALATH If we're honest with ourselves, most of us know the one thing we lack. CRAIG GROESCHEL I'm about to do something very clever and a tiny bit against the rules of the universe. It's importa... TOMMY DONBAVAND We are hell different but vanity keeps us stuck. PARUL WADHWA Beauty fades, but knowledge is eternal ANDREW FAIRCHILD Wherever you are, be there. If you can be fully present now, you’ll know what it means to live. STEVE GOODIER We believe the high number of violations is attributable to a significant increase in enforcement st... BEN HATFIELD Everything passes by, and we are left with just our memories BEN OAK We believe that this tax rate, at 20 percent, is a significant increase in tax and may lead us to no... RICHARD OWEN The mice recovered a lot of their normal movement. MARC G. CARON By studying this marker we have a better chance to identify the patients who are more likely to have... EDWARD KEENAN Abstract conversations are my favourite, for they unviel true convictions. PARUL WADHWA He wept because he was afraid now that he could not save Gabriel. He no longer cared about himself LOIS LOWRY This study provides encouragement to all American men who are concerned about prostate cancer. Accum... JOYCE NETTLETON We wanted to increase production, have better control over the various mix designs we produce, lower... GREG ROHLF Adult obesity and overweight statistics have increased by about 50 percent since the Dietary Goals w... LARRY MCCLEARY I think that many people will intentionally overlook all of the lifeless facts about their relations... C. JOYBELL C. Against this background we are confident of our earlier expectations that we will be able to grow pr... HENNING KAGERMANN Here is one fact 1 minute to finish the class, 1 day to die, one day behind that fact, one day in th... DEYTH BANGER There is an abundance of animal research that indicates if you eat far below your caloric maintenanc... MADELYN FERNSTROM All of us can expect to live longer than any organization that we would work for. That continues apa... DAN PINK One of the potential uses we envision is to use the ART treatment as a way to use tumor components t... DAVID MCKEAN One of the potential uses we envision is to use the ART treatment as a way to use tumor components t... DAVID MCKEAN There's a significant number of the staff, the normal, assigned staff, that no longer have homes to ... HARRY BAILEY With the combined benefits of radiation, chemotherapy and liver transplantation, our patients with b... CHARLES ROSEN The great increase in longevity has produced a surge in the desire to accumulate assets for retireme... WILLIAM VICKREY The more we give, the more we reap the benefits of feeling good in helping others. We are all capabl... ANGIE KARAN I think I'm basically a liberal Conservative - I believe in low tax, spirit of free enterprise, ... BORIS JOHNSON The truth is, it's really only okay to be yourself if that self is within an accepted range of 'norm... STACEY KADE Not everyone has the time to be normal. LJUPKA CVETANOVA I want the presence of God Himself, or I don't want anything at all to do with religion... I want al... A.W. TOZER The biggest potential and actual crises of the 21st century all have a strong, long, slow aspect wit... JAMAIS CASCIO If you pour everything you have into this life, this world, which is temporary and fading, you're je... CRAIG GROESCHEL The secret to longevity, as I see it, has less to do with diet, or even exercise, and more to do wit... DAN BUETTNER Fear not, we are of the nature of the lion, and cannot descend to the destruction of mice and such s... ELIZABETH I The first rule on breaking a rule is to know everything about the rule. NUNO ROQUE If we all look at life we think how nice, then we look at death and everybody goes oh you can say th... GARY F EVANS... If you love someone you must set them free like the wind and give them the respect they deserve.If y... GARY F EVANS... If some plan removes that water and we no longer have that warming effect, we're in a real pickle. AL KALIN Absoballylutely top hole, wot. A and B the C of D I'd say. . . Above and Beyond the Call of Duty. BRIAN JACQUES We believe the high number of violations is attributable to a significant increase in enforcement st... BEN HATFIELD Some people never take a chance and never know what it's like to live life to the full. CHLOE THURLOW Entrepreneur, you're either raising the bar of excellence or, you're exhaling at the bar which is ex... ONYI ANYADO I live my life progressing for nothing else but the best. JONATHAN ANTHONY BURKETT We need to embrace every day and enjoy it as much as we can. KAREN TODD SCARPULLA We kind of felt with the people we had coming back that if we just came out and kept getting better ... BRIAN CROSS The reality is we know exactly how to do that in mice and no idea how to do that in people. DR. ROBERT WOOD I was at ease in everything, to be sure, but at the same time satisfied with nothing. Each joy made ... THE FALL The shortest and surest way to live with honour in the world, is to be in reality what we would appe... SOCRATES Tim's characters tend to wear darker colors and some, like the corpse bride, are no longer living, b... JOHN AUGUST Tim's characters tend to wear darker colors and some, like the corpse bride, are no longer living, b... JOHN AUGUST Clay in the hands of a good potter suffers so many good turns, but in the end, we see its real and t... ERNEST AGYEMANG YEBOAH You must save what you can of your life; you musn't lose it all simply because you've lost a part. HENRY JAMES You're afraid of getting hurt like I'm afraid to die. It doesn't mean I'm not going to live every da... VI KEELAND I realized that more and more I was saying, 'It seems to me that we have come to the time war ought ... LINUS PAULING The longer I live the more convinced I become that God governs in the affairs of men. And have we no... BENJAMIN FRANKLIN A new day is here! yesterday is gone! tomorrow is preparing to come! but why is today here? ERNEST AGYEMANG YEBOAH Overall, the focus has been at the substations, and we have seen a significant decrease in the numbe... ART PEREZ Sometimes it took death for me to see life, don't live with regrets keep your head high. In a ... PUERTO RICAN PRINCESS If they haven't gone back to work by Thursday, then we're going to have a very significant penalty p... MICHAEL HANCOCK I'd probably live a few years longer if we had more of them. ANDY MURRAY the room of the spirit is the mind and the seat of the spirit is the heart. What we give room to muc... ERNEST AGYEMANG YEBOAH
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